Testosterone P Radjay Healthcare & Pharmaceutical 250 mg/ml


Substance: Testosterone PropionatePackage: vial (250 mg/ml)


The commercial name of the drug

Testosterone P

International nonproprietary name of active agents



1 ml of solution contains:

active substance: testosterone propionate 100 mg;

excipients: benzyl alcohol, benzyl benzoate, peach oil.


Transparent oily solution of light yellow to yellow color, with characteristic odor.

Dosage form

Solution for injection oil.


Androgenic hormone G03B A03.


Pharmacodynamic properties

Testosterone is the primary male sexual hormone, synthesized and secreted by the testicles. It stimulates the growth and development of male sex organs and secondary sex characteristics (maturation of prostate, seminal vesicles, penis and scrotum), the distribution of hair in male pattern on the face, pubis, Breasts), the development of the larynx, the muscles of the body and distribution of fat. Delays nitrogen, sodium, potassium and phosphorus, increases anabolism and decreases protein catabolism. A premature increase in the concentration of testosterone in the blood plasma in the period before puberty causes epiphyseal closure and the suspension of growth. Stimulates the production of erythropoietin and red blood cells. The negative feedback mechanism (feedback) inhibits the secretion of luteinizing and follicle stimulating hormones of the pituitary gland and inhibits spermatogenesis.

testosterone propionate has biological and therapeutic properties of the natural hormone, but more slowly absorbed and more racks in the body than testosterone. Testosterone propionate appoint mainly men with sexual underdevelopment, functional disorders in the reproductive system, menopausal syndrome, with acromegaly. In some cases, testosterone propionate has a positive effect on hypertrophy of the prostate: General condition improves, decrease urinary disorders, etc. Testosterone propionate may also have a positive effect in the angioneurotic form of angina. The positive effects associated with improving blood circulation and metabolic processes in cardiac muscle; there are also favorable changes in the lipid ratio in the blood, the increase of the coefficient lecithin/cholesterol.

The introduction of testosterone propionate women causes inhibition of gonadotropic pituitary function, oppression of function of ovarian reserve and ovarian, endometrial atrophy, suppression of the function of mammary glands. Shows a beneficial effect in complaints of menopause.

The pharmacokinetic properties.

Testosterone propionate starts its action immediately after the injection and lasts for 24 hours In the blood about 98% of testosterone is bound to a specific fraction of globulin that binds testosterone and estradiol. Biotransformation occurs in the liver to various 17-ketosteroids, which, after conjugation with glucuronic or sulfuric acid are excreted in the urine (approximately 90%). About 6% absorbirowawrzayasa of the drug is excreted in the feces in an unbound form.


In men, androgenic insufficiency after castration, evnuhoidizm, impotence hormonal origin, symptoms of male climax (decreased libido, mental and physical activity), in acromegalic patients; prostatic hypertrophy; osteoporosis caused by androgenic insufficiency; angioneurotic form of angina.

In women with climacteric vascular and neurological disorders in cases where contraindicated estrogenic drugs (with tumors of genitals and mammary glands, uterine bleeding); concurrently with radiation therapy for cancer of the breast and ovarian cancer (usually in women under the age of 60 years); at dysfunctional uterine bleeding in older women.


Intramuscularly deep into the gluteal muscle. Dose set individually depending on indications and the patient’s response.

Men with evnuhoidizme, congenital underdevelopment gonads, removing them surgically or due to trauma, and also in acromegalic patients prescribed 25 mg daily or 50 mg every other day or every 2 days. The duration of treatment depends on the effectiveness of therapy and the nature of the disease. Usually the treatment is carried out for a long time. After improvement of the clinical picture of injected testosterone propionate in maintenance doses: 5-10 mg daily or every other day.

If impotence due to functional deficiency sex glands, fatigue and nervous exhaustion, as well as male menopause syndrome appoint 10 mg daily or 25 mg 2-3 times a week for 1-2 months.

When prostatic hypertrophy in the initial stage of taking 10 mg a day for 1-2 months.

In patients with angina sometimes there is a positive effect in the use of testosterone for 10 – 12.5 mg 1 time per week; if well tolerated, the number of injections was increased to two a week (for 3 5 weeks). By the end of treatment, the dose and number of injections is again reduced. The course of treatment consists of 15-20 injections.

Women over 45 years old with dysfunctional uterine bleeding prescribe 10-25 mg a day for 20-30 days to stop bleeding and the appearance of atrophic cells in the vaginal smears. Preliminary it is necessary to exclude malignant neoplasms of the uterus.

In vascular and neurological disorders of climacteric origin in females and the presence of contraindications to the use of estrogen, injected testosterone propionate 10 mg every other day 25 mg 2 times a week for 2-3 weeks.

In malignant breast tumors or ovarian testosterone propionate is administered at a dose of 50 mg daily for several months, then (depending on the results of treatment), reduce the dose and for a long time prescribed maintenance doses. As a Supplement to surgery or radiation therapy the drug is prescribed to women to 60 years (older women are advised to take estrogen).

Higher doses of adult intramuscularly: single 50 mg daily 100 mg.

The drug should not be administered intravenously!