Active component: Tadalafil.
Product form: 20 tablets in blister 20mg.
Color tablets: white with a pink tinge.
Drug for treatment of erectile dysfunction. Is a reversible selective inhibitor of specific phosphodiesterase type 5 (PDE5) cGMP. When sexual stimulation causes local release of nitric oxide, inhibition of PDE5 tadalafil leads to increased levels of cGMP in the cavernous body of penis. The result is relaxation of smooth muscles of arteries and blood flow to the tissues of the penis that causes erections. Tadalafil has no effect without sexual stimulation.
Cialis improves erection and the possibility of successful sexual intercourse. Esculap Balkan Pharmaceuticals 20mg acts during 36 hours. The effect is already apparent 16 minutes after taking the drug in the presence of sexual arousal.Tadalafil in healthy individuals does not cause significant changes in systolic and diastolic pressures compared to placebo in supine position (mean maximum reduction is 1.6/0.8 mm Hg . St ., respectively ) and in standing position (mean maximum decrease of 0.2/4.6 mm Hg . St ., respectively ). Esculap Balkan Pharmaceuticals 20mg does not cause significant changes in heart rate.Tadalafil does not cause changes in the recognition of colors (blue /green ), due to its low affinity for PDE 6. In addition, there is no influence of tadalafil on visual acuity, electroretinogram, intraocular pressure and pupil size. In the study of tadalafil in men in the daily dose of 10 mg, no clinically significant effect of the drug on the amount and concentration of sperm, motility and morphology of sperm.
The middle-aged men to take the drug at a dose of 20 mg. doctor take at least 16 minutes before anticipated sexual activity, regardless of the meal. Patients can carry out attempt of sexual intercourse at any time within 36 hours after taking the drug in order to establish the optimal response time to receive the drug.
The maximum recommended frequency of reception – 1 time/day.